tumours represent a complex "ecosystem," which beside difficult-to-treat cancer
cells consists of numerous other, non-cancerous cells supporting the cancer
cells. These "supporting" cells have significant effects on the growth of
virtually all types of solid tumours and their spread throughout the patient's
So far, treatment of malignant tumours has been dominated by the attempts to target the cancer cell itself. However, a therapeutic intervention into an auxiliary component of the tumour ecosystem may have far-reaching consequences for the cancer cells themselves, potentially leading to a far better therapeutic outcome of the patient.
Some of the findings obtained recently by the members of the investigation team on the mechanism of functioning and targeted interventions into this supporting tumour microenvironment are very promising and have already been patented. Thus, they may lead to an entirely novel approach to the treatment of malignancies.