Publications

NEW     CANCER GENOMICS & PROTEOMICS; May-Jun 2021; 18
Štěpán Novák, Michal Kolář, Arpád Szabó, Zdena Vernerová, Lukáš Lacina, Hynek Strnad, Jana Šáchová, Miluše Hradilová, Jan Havránek, Michal Španko, Matúš Čoma, Lukáš Urban, Miriam Kaňuchová, Nikola Melegová, Robert Gürlich, Josef Dvořák, Karel Smetana Jr, Peter Gál, Pavol Szabo
Desmoplastic Crosstalk in Pancreatic Ductal Adenocarcinoma Is Reflected by Different Responses of Panc-1, MIAPaCa-2, PaTu-8902, and CAPAN-2 Cell Lines to Cancer-associated/Normal Fibroblasts

The Journal of Immunology; April 20, 2021
Alena Moudrá, Veronika Niederlová, Jiří Novotný, Lucie Schmiedová, Jan Kubovčiak, Tereza Matejková, Aleš Drobek, Michaela Přibíková, Romana Stopková, Dagmar Čížková, Aleš Neuwirth, Juraj Michalík, Kateřina Křížová, Tomas Hudcovic, Michal Kolář, Hana Kozáková, Jakub Kreisinger, Pavel Stopka, Ondřej Štěpánek
Phenotypic and Clonal Stability of Antigen-Inexperienced Memory-like T Cells across the Genetic Background, Hygienic Status, and Aging)

CHEMICAL BIOLOGY & DRUG DESIGN, Wiley Online Library; February 2021, Volume: 97
Nikita Abramenko, Zdeněk Kejík, Robert Kaplánek, Ameneh Tatar, Tereza Brogyányi, Martina Pajková, David Sýkora, Kateřina Veselá, Veronika Antonyová, Petr Dytrych, Masao Ikeda-Saito, Pavel Martásek, Milan Jakubek
Spectroscopic study of in situ-formed metallocomplexes of proton pump inhibitors in water

International Journal of Molecular Sciences; 2021, 22(2), published 11. 1. 2021
Zdeněk Kejík, Robert Kaplánek, Michal Masařík, Petr Babula, Adam Matkowski, Petr Filipenský, Kateřina Veselá, Jakub Gburek, David Sýkora, Pavel Martásek, Milan Jakubek
Iron Complexes of Flavonoids-Antioxidant Capacity and Beyond

Folia Biologica; 66, 142-147 (2020)
V. Lachová, P. Mitrengová, N. Melegová, K. Smetana JR., P. Gál
Genistein Induces Bcl-2 Expression in Human Dermal Microvascular Endothelial Cells: a Short Report

Frontiers in Cellular Neuroscience; 2021, Volume 14, January 28, 2021
Jakub Červenka, Jiřina Tylečková, Helena Kupcová Skalníková, Kateřina Vodičková Kepková, Levgeniia Poliakh, Ivona Valeková, Lucie Pfeiferová, Michal Kolář, Michaela Vaškovičová, Tereza Pánková and Petr Vodička
Proteomic Characterization of Human Neural Stem Cells and Their Secretome During in vitro Differentiation 

International Journal of Molecular Sciences; 2021, 18. January 2021
Matúš Čoma, Lucia Fröhlichová, Lukáš Urban, Robert Zajíček, Tomáš Urban, Pavol Szabo, Štěpán Novák, Vitaly Fetissov, Barbora Dvořánková, Karel Smetana Jr., Peter Gál
Molecular Changes Underlying Hypertrophic Scarring Following Burns Involve Specific Deregulations at AllWound Healing Stages (Inflammation, Proliferation and Maturation) 

Molecular Medicine Reports; 2021, accepted October 2, 2020
Peter Gál, Tomáš Vasilenko, Ivan Kováč, Matúš Čoma, Ján Jakubčo, Martina Jakubčová, Vlasta Peržeľová, Lukáš Urban, Michal Kolář, František Sabol, Ján Luczy, Martin Novotný, Jaroslav Majerník, Hans-Joachim Gabius, Karel Smetana Jr
Human galectin‑3: Molecular switch of gene expression in dermal fibroblasts in vitro and of skin collagen organization in open wounds and tensile strength in incisions in vivo

Cancers; 2020, Volume 12, Issue 11, 3324, 2020/11/10
Jiří Novotný, Karolína Strnadová, Barbora Dvořánková, Šárka Kocourková, Radek Jakša, Pavel Dundr, Václav Pačes, Karel Smetana Jr., Michal Kolář a Lukáš Lacina
Single-Cell RNA Sequencing Unravels Heterogeneity of the Stromal Niche in Cutaneous Melanoma Heterogeneous Spheroids

International Journal of Molecular Sciences; 26 October 2020
Jan Brábek, Milan Jakubek, Fréderic Vellieux, Jiří Novotný, Michal Kolář, Lukáš Lacina, Pavol Szabo, Karolína Strnadová, Daniel Rösel, Barbora Dvořánková and Karel Smetana Jr.
Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19

Journal of Experimental & Clinical Cancer Research; Article number 163; 2020
Madiha Kanwal, Michal Šmahel, Mark Olsen, Jana Šmahelová, Ruth Tachezy
Aspartate β-hydroxylase as a target for cancer therapy

in vivo; September-October 2020 vol. 34
Karel Smetana Jr., Daniel Rösel, Jan Brábek
Raloxifene and Bazedoxifene Could Be Promising Candidates for Preventing the COVID-19 Related Cytokine Storm, ARDS and Mortality

Cancers; 3 September 2020
Karel Smetana Jr., Lukáš Lacina, Ondřej Kodet
Targeted Therapies for Melanoma 

Cancers; 28 August 2020
Aneta Gandalovičová, Anna-Marie Šůchová, Vladimír Čermák, Ladislav Merta, Daniel Rösel, Jan Brábek
Sustained Inflammatory Signalling through Stat1/Stat2/IRF9 Is Associated with Amoeboid Phenotype of Melanoma Cells

International Journal of Oncology; 26 June 2020
Ondřej Kodet, Jan Kučera, Karolína Strnadová, Barbora Dvořánková, Jiří Štork, Lukáš Lacina, Karel Smetana Jr
Cutaneous melanoma dissemination is dependent on the malignant cell properties and factors of intercellular crosstalk in the cancer microenvironment (Review) 

Scientific Data; Volume 7 no. 160; 27 May 2020
Vladimír Čermák, Aneta Gandalovičová, Ladislav Merta, Karel Harant, Daniel Rösel, Jan Brábek
High-throughput transcriptomic and proteomic profiling of mesenchymal-amoeboid transition in 3D collagen

European Journal of Cell Biology; Volume 99; May 2020
Vladimír Čermáka, Vojtěch Dostál, Michael Jelínek, Lenka Libusová, Jan Kovář, Daniel Rösel, Jan Brábek
Microtubule-targeting agents and their impact on cancer treatment

IN VIVO; 2020 vol. 34 no. 3
Karel Smetana Jr., Jan Brábek
Role of Interleukin-6 in Lung Complications in Patients with COVID-19: Therapeutic Implications

Anticancer Research International Journal of Cancer Research and Treatment; 2020, April 23
Lenka Varinská, Lenka Fáber, Eva Petrovová, Ludmila Balážová, Eleonóra Ivančová, Michal Kolář a Peter Gál
Galectin-8 Favors VEGF-Induced Angiogenesis: In Vitro Study in Human Umbilical Vein Endothelial Cells and In Vivo Study in Chick Chorioallantoic Membrane

Biochimica et Biophysica Acta; Volume 1868, Issue 7; Online 6 April 2020
Adéla Šimková, Petr Bušek, Aleksi Šedo, Jan Konvalinka
Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications 

Histochemistry and Cell Biology; 30 March 2020
Karolína Strnadová, Michal Španko, Barbora Dvořánková, Lukáš Lacina, Ondřej Kodet, Andrej Shbat, Ivo Klepáček, Karel Smetana Jr
Melanoma xenotransplant on the chicken chorioallantoic membrane: a complex biological model for the study of cancer cell behaviour 

Cancer; 2020, 11/1
Kateřina Strouhalová, Magdaléna Přechová, Aneta Gandalovičová, Jan Brábek, Martin Gregor, Daniel Rösel
Vimentin Intermediate Filaments as Potential Target for Cancer Treatment 

Cancer; 2020, 12/4
Jiří Novotný, Veronika Bandúrová, Hynek Strnad, Martin Chovanec, Miluše Hradilová, Jana Šáchová, Martin Šteffl, Josipa Grušanović, Roman Kodet, Václav Pačes, Lukáš Lacina, Karel Smetana Jr., Jan Plzák, Michal Kolář, Tomáš Vomastek
Analysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas and Paired Normal Mucosae Reveals Cyclin D1 Deregulation and Compensatory Effect of Cyclin D2

British Journal of Cancer; 8/2019
Michael Fernandes, Daniel Rosel, Jan Brábek
Solid cancer: the new tumour spread endpoint opens novel opportunities

Viruses; 12/2019
Barbora Pokrývková, Martina Saláková, Jana Šmahelová, Zuzana Vojtěchová, Vendula Novosadová, Ruth Tachezy
Detailed Characteristics of Tonsillar Tumors with Extrachromosomal or Integrated Form of Human Papillomavirus

Oncology Reports; 12/2019

Karolína Lhotaková, Adrianna Grzelak, Ingrid Poláková, Julie Vacková, Michal Šmahel
Establishment and characterization of a mouse tumor cell line with irreversible downregulation of MHC class I molecules

BIOPROSPECT; 29th Volume, No. 4/2019
Peter Vanek, Helena Kupcová Skalníková
EXTRACELULÁRNÍ VÁČKY A JEJICH BIOMEDICÍNSKÝ POTENCIÁL 

GENES - Open Access Journal; 9. 11. 2019
Vratislav Horák, Anna Palanová, Jana Čížková, Veronika Miltrová, Petr Vodička, Helena Kupcová Skalniková
Melanoma-Bearing Libechov Minipig (MeLiM): The Unique Swine Model of Hereditary Metastatic Melanoma

BIOPROSPECT; 29th Volume, No. 3/2019
Anna Palánová, Helena Kupcová Skalníková
NEKÓDUJÍCÍ RNA A MALIGNÍ MELANOM 

ONCOLOGY REPORTS; 17. 9. 2019 
Jan Kučera, Karolína Strnadová, Barbora Dvořánková, Lukáš Lacina, Ivana Krajsová, Jiří Štork, Hana Kovářová, Helena Kupcová Skalníková, Petr Vodička, Jan Motlík, Pavel Dundr, Karel Smetana, Ondřej Kodet
Serum proteomic analysis of melanoma patients with immunohistochemical profiling of primary melanomas and cultured cells: Pilot study

Folia Biologica; 2019
I. Šušaníková, M. Puchľová, V. Lachová, E. Švajdlenka, P. Mučaji, K. Smetana Jr., P. Gál
Genistein and Selected Phytoestrogen-Containing Extracts Differently Modulate Antioxidant Properties and Cell Differentiation: an in Vitro Study in NIH-3T3, HaCaT and MCF-7 Cells